Key Findings

The study identified several AMR genes and mutations in 141 clinical Helicobacter pylori isolates from Eastern China, including 23S rRNA (A2143G), infB (C110T), gyrA (T261A), gyrB (G1033A), pbp1A (1785_1786insAGC), rdxA (G278A), frxA (T184A), recA (G946A), 16S rRNA (A928C), and oorD (G22A) associated with resistance to clarithromycin, levofloxacin, amoxicillin, metronidazole, tetracycline, and furazolidone.