Evolution and maintenance of a large multidrug-resistant plasmid in a Salmonella enterica Typhimurium host under differing antibiotic selection pressures.

PMID: 394361442024China

Key Findings

The study characterizes the evolution of a large multidrug-resistant plasmid (pJXP9) in Salmonella enterica Typhimurium under varying antibiotic selection pressures, identifying several AMR genes and mutations that contribute to resistance and plasmid maintenance.

View on PubMed

5gene entries

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCTX-M	1	beta-lactam resistance	Cefotaxime	Salmonella enterica serovar Typhimurium	Reslit	-
floR	1	fluoroquinolone resistance	Florfenicol	Salmonella enterica serovar Typhimurium	Reslit	-
fosA	1	fosfomycin resistance	Fosfomycin	Salmonella enterica serovar Typhimurium

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
arcA	S104P	AGT->CCC	-	Salmonella enterica	Ciprofloxacin\|Colistin	Reslit	-

Browse Papers

Evolution and maintenance of a large multidrug-resistant plasmid in a Salmonella enterica Typhimurium host under differing antibiotic selection pressures.

AMR Genes

AMR Mutations