Key Findings

The study identified several AMR genes and mutations in drug-resistant Salmonella Typhi isolates from children, including bla_CTXM15, bla_TEM1B, qnrS1, aac6'Ia, catA1, dfrA7, sul1, qacEΔ1, and the gyrA_S83F mutation, which are associated with resistance to various antibiotics such as ciprofloxacin, ampicillin, chloramphenicol, and sulfamethoxazole.