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Key Findings
The study identifies the bla NDM-1 gene as a major cause of carbapenem resistance in Vibrio fluvialis isolates from Kolkata, India. Several additional resistance genes, including aadA1, aadB, aac(6')-Ib-cr, sul1, sul3, floR, bla OXA-1, bla OXA-7, bla OXA-9, bla TEM-9, bla CTX-M-3, strA, and tetB, were also characterized.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(6')-Ib-cr | 1 | acetyltransferase | - |
| Reslit | - |
| aadA1 | 1 | adenyltransferase | Streptomycin |
| Reslit | - |
| aadA2 | 1 | adenyltransferase | Streptomycin |
| Reslit |
| - |
| aadB | 1 | adenyltransferase | - |
| Reslit | - |
| blaCTX-M | 1 | beta-lactamase | Cephalosporin |
| Reslit | - |
| blaNDM | 1 | beta-lactamase | Carbapenem |
| Reslit | - |
| blaOXA | 3 | beta-lactamase | AmpicillinCeftriaxoneCefotaximeImipenemCarbapenem |
| Reslit | - |
| blaTEM | 1 | beta-lactamase | - |
| Reslit | - |
| floR | 1 | efflux pump | Chloramphenicol |
| Reslit | - |
| sul1 | 1 | dihydropteroate synthase | Sulfonamide |
| Reslit | - |
| sul3 | 1 | dihydropteroate synthase | Sulfonamide |
| Reslit | - |
| tetB | 1 | tetracycline efflux pump | Tetracycline |
| Reslit | - |
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