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Key Findings
The study identified multiple AMR genes and chromosomal mutations in multidrug-resistant Salmonella enterica serovar Kentucky ST198 isolates from Algeria, including bla TEM-1B, bla CTX-M-15, aac(3)-Id, aadA7, sul1, tet(A), mph(A), qnrB19, cmlA1, and floR, along with mutations in gyrA and parC genes that confer resistance to ciprofloxacin.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(3)-Id | 1 | aminoglycoside acetyltransferase | GentamicinKanamycin |
| Reslit | - |
| aadA7 | 1 | adenine phosphoribosyltransferase | StreptomycinSpectinomycin |
| Reslit | - |
| blaCMY | 2 | cephamycinase |
Cefotaxime |
|
Reslit |
| - |
| blaCTX-M | 1 | extended-spectrum beta-lactamase | Cefotaxime |
| Reslit | - |
| blaTEM | 3 | penicillinase | Ampicillin |
| Reslit | - |
| cmlA1 | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| floR | 1 | multidrug efflux pump | Chloramphenicol |
| Reslit | - |
| mph(A) | 1 | macrolide phosphotransferase | Azithromycin |
| Reslit | - |
| qnrB | 1 | quinolone resistance protein | Ciprofloxacin |
| Reslit | - |
| sul1 | 1 | sulfonamide resistance protein | Sulfamethoxazole |
| Reslit | - |
| tet(A) | 1 | tetracycline efflux pump | Tetracycline |
| Reslit | - |
| - |
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