Mycobacterium tuberculosis Lineages Associated with Mutations and Drug Resistance in Isolates from India.

PMID: 354420782022

0gene entries

30mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pncA	T76P	-	-	Mycobacterium tuberculosis	Pyrazinamide	Reslit	-
inhA	I21T	-	-	-	Ethionamide	Reslit	-
embB	T1082A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
gyrA	A90V	-	-	-	Fluoroquinolones	Reslit	-
rpsL	K88R	-	-	-	Streptomycin	Reslit	-
katG	S315X	-	-	Mycobacterium tuberculosis	Isoniazid	Reslit	-
rpoB	S450X	-	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
embB	Q497R	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
pncA	L27P	-	-	Mycobacterium tuberculosis	Pyrazinamide	Reslit	-
rpsL	K43R	-	-	-	Streptomycin	Reslit	-
inhA	S94A	-	-	-	Ethionamide	Reslit	-
rpoB	H445X	-	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
embB	G406X	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
gyrA	D94X	-	-	-	Fluoroquinolones	Reslit	-
pncA	G132A	-	-	Mycobacterium tuberculosis	Pyrazinamide	Reslit	-
rpoB	L430P	-	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
rpoB	Q432L	-	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
embB	D1024N	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
embB	M306X	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
rpoB	D435X	-	-	Mycobacterium tuberculosis	Rifampicin	Reslit	-
pncA	I5S	-	-	Mycobacterium tuberculosis	Pyrazinamide	Reslit	-
embB	D354A	-	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
rrs	-	A1401G	-	-	Aminoglycoside	Reslit	-
rrs	-	A514C	-	-	Streptomycin	Reslit	-
fabG1	-	C-15T	-	-	Isoniazid	Reslit	-
inhA	-	C-15T	-	-	Isoniazid	Reslit	-
embA	-	C36T	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
fabG1	-	C46T	-	-	Ethionamide	Reslit	-
embA	-	C48T	-	Mycobacterium tuberculosis	Ethambutol	Reslit	-
rrs	-	C517T	-	-	Streptomycin	Reslit	-