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Key Findings
The study identified various AMR genes and mutations in Enterococcus faecalis isolates from macaque cephalic implants, highlighting the presence of high-level aminoglycoside resistance, tetracycline resistance, and bacitracin resistance. These findings emphasize the complexity of AMR in clinical settings and the need for targeted antimicrobial strategies.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(6') | 1 | aminoglycoside acetyltransferase and phosphotransferase | Gentamicin |
| Reslit | - |
| aac(6')-Ib | 1 | aminoglycoside modifying enzyme | Streptomycin |
| Reslit | - |
| aph(3')-IIIa | 1 | aminoglycoside phosphotransferase | NeomycinKanamycin |
|
Reslit |
| - |
| bcrA | 1 | ATP-binding cassette transporter | Bacitracin |
| Reslit | - |
| bcrB | 1 | ATP-binding cassette transporter | Bacitracin |
| Reslit | - |
| bcrR | 1 | transcriptional regulator | Bacitracin |
| Reslit | - |
| catA1 | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| dfrG | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| erm(B) | 1 | erythromycin ribosome methyltransferase | ErythromycinClindamycin |
| Reslit | - |
| lsa(A) | 1 | macrolide-lincosamide-streptogramin B resistance protein | ErythromycinClindamycinLincomycinStreptogramin b |
| Reslit | - |
| str | 1 | streptomycin phosphotransferase | Streptomycin |
| Reslit | - |
| tet(L) | 2 | tetracycline resistance protein | TetracyclineDoxycyclineOxytetracycline |
| Reslit | - |
| tet(M) | 2 | tetracycline resistance protein | TetracyclineDoxycyclineOxytetracycline |
| Reslit | - |
| tet(S) | 2 | tetracycline efflux pump | TetracyclineDoxycyclineOxytetracycline |
| Reslit | - |
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