Key Findings

The study identifies multiple AMR genes and mutations in Australian E. coli ST131 isolates, including bla CTX-M-15 and bla CTX-M-27 for beta-lactam resistance, aadA5, strA, strB, mphA, dfrA17, sul1, qacEΔ1, and chrA for resistance to aminoglycosides, macrolides, trimethoprim, sulfonamides, quaternary ammonium compounds, and chromate. Fluoroquinolone resistance mutations in gyrA and parC were also found.