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Explore scientific publications on antimicrobial resistance
Key Findings
The study identified various antimicrobial resistance genes in Salmonella isolates from Nigerian poultry, including aac(6')-Ia, aac(6')-Ib, aadA7, aph(3")-Ia, aph(3")-Ib, aph(6')-Id, aph(6')-Ic, aac(3)-Ia, aac(3)-IIa, aac(3)-IVa, aac(6')-IIa, aac(3)-Id, sul1, sul2, sul3, tet(A), tet(M), qnrS1, qnrB19, blaTEM, dfrA14, dfrA15, dfrA17, catA1, cmlA1, and floR. Mutations in gyrA (Ser83Phe, Asp87Tyr) and parC (Thr57Ser, Ser80Ile) were also associated with resistance to nalidixic acid and ciprofloxacin.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(3)-Ia | 1 | aminoglycoside acetyltransferase | Gentamicin |
| Reslit | - |
| aac(3)-Id | 1 | aminoglycoside acetyltransferase | Gentamicin |
| Reslit | - |
| aac(3)-IIa |
| aminoglycoside acetyltransferase |
Gentamicin |
|
Reslit |
| - |
| aac(3)-IVa | 1 | aminoglycoside acetyltransferase | Gentamicin |
| Reslit | - |
| aac(6')-Ia | 1 | aminoglycoside modifying enzyme | Kanamycin |
| Reslit | - |
| aac(6')-Ib | 1 | aminoglycoside modifying enzyme | Kanamycin |
| Reslit | - |
| aac(6')-IIa | 1 | aminoglycoside acetyltransferase | Gentamicin |
| Reslit | - |
| aadA7 | 1 | adenine phosphotransferase | StreptomycinSpectinomycin |
| Reslit | - |
| aph(3'')-Ib | 1 | aminoglycoside phosphotransferase | KanamycinGentamicin |
| Reslit | - |
| aph(3')-Ia | 1 | aminoglycoside phosphotransferase | KanamycinGentamicin |
| Reslit | - |
| aph(6)-Ic | 1 | aminoglycoside phosphotransferase | KanamycinGentamicin |
| Reslit | - |
| aph(6)-Id | 1 | aminoglycoside phosphotransferase | KanamycinGentamicin |
| Reslit | - |
| blaTEM | 1 | beta-lactamase | Ampicillin |
| Reslit | - |
| catA1 | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| cmlA1 | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| dfrA14 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| dfrA15 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| dfrA17 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| floR | 1 | florfenicol resistance protein | Chloramphenicol |
| Reslit | - |
| qnrB | 1 | quinolone resistance protein | Ciprofloxacin |
| Reslit | - |
| qnrS | 1 | quinolone resistance protein | Ciprofloxacin |
| Reslit | - |
| tet(A) | 1 | tetracycline efflux pump | Tetracycline |
| Reslit | - |
| tet(M) | 1 | tetracycline ribosomal protection protein | Tetracycline |
| Reslit | - |
| - |
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