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Explore scientific publications on antimicrobial resistance
Explore scientific publications on antimicrobial resistance
Key Findings
The study reports an outbreak of NDM-1-producing Klebsiella pneumoniae in an ICU during the COVID-19 pandemic, highlighting the presence of multiple AMR genes including blaNDM-1, blaTEM-1, blaCTX-M-15, blaOXA-1, blaCMY-4, and others, along with mutations in ParC and GyrA contributing to quinolone resistance.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(3)-I | 1 | aminoglycoside modifying enzyme | Aminoglycoside |
| Reslit | - |
| aac(6')-Ib-cr | 1 | aminoglycoside modifying enzyme | Aminoglycoside | - | Reslit | - |
| aph(3')-VI | 1 | aminoglycoside modifying enzyme | Aminoglycoside |
|
Reslit |
| - |
| aph(6)-Ia | 1 | aminoglycoside modifying enzyme | Aminoglycoside |
| Reslit | - |
| blaCMY | 1 | beta-lactamase | - |
| Reslit | - |
| blaCTX-M | 1 | beta-lactamase | - |
| Reslit | - |
| blaNDM | 1 | carbapenemase | Carbapenem |
| Reslit | - |
| blaOXA | 1 | beta-lactamase | - |
| Reslit | - |
| blaTEM | 1 | beta-lactamase | - |
| Reslit | - |
| catA1 | 1 | chloramphenicol acetyltransferase | Phenicol |
| Reslit | - |
| dfrA14 | 1 | dihydrofolate reductase | Trimethoprim |
| Reslit | - |
| floR | 1 | efflux pump | Phenicol |
| Reslit | - |
| fosA | 1 | fosfomycin resistance protein | Fosfomycin |
| Reslit | - |
| mdfA | 1 | efflux pump | Macrolide |
| Reslit | - |
| sul1 | 1 | dihydropteroate synthase | Sulfonamide |
| Reslit | - |
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