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Explore scientific publications on antimicrobial resistance
Explore scientific publications on antimicrobial resistance
Key Findings
This study identifies multiple AMR genes and mutations in Clostridioides difficile, including ermB, tetM, mefH, and various mutations in gyrA, gyrB, rpoB, pbp1, and pbp3. These findings highlight the widespread nature of AMR in C. difficile and its potential role in the spread of the bacterium.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(6') | 1 | aminoglycoside modifying enzyme | Aminoglycoside |
| Reslit | - |
| catP | 1 | chloramphenicol acetyltransferase | Chloramphenicol |
| Reslit | - |
| cfr(B) | 1 | peptidyl transferase | Oxazolidinone |
|
Reslit |
| - |
| erm(52) | 1 | methyltransferase | MacrolideLincosamideStreptogramin b |
| Reslit | - |
| erm(B) | 1 | methyltransferase | MacrolideLincosamideStreptogramin b |
| Reslit | - |
| erm(G) | 1 | methyltransferase | MacrolideLincosamideStreptogramin b |
| Reslit | - |
| mef(H) | 1 | macrolide efflux protein | Macrolide |
| Reslit | - |
| sat4 | 1 | adenylyltransferase | Aminoglycoside |
| Reslit | - |
| tet(40) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
| tet(44) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
| tet(M) | 1 | ribosomal protection protein | Tetracycline |
| Reslit | - |
| - |
| H502N | - | - | - | Rifamycin | Reslit | - |
| R505K | - | - | - | Rifamycin | Reslit | - |
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