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Antimicrobial Resistance Mechanisms and Molecular Detection Techniques

PMID: 115857882023Europe|North America|Asia

Key Findings

The paper discusses molecular detection methods for antimicrobial resistance, focusing on genes like mecA and blaZ, which confer resistance to beta-lactam antibiotics in staphylococci.

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27gene entries
0mutation entries

AMR Genes

Gene NameEncodesConfers Resistance ToOrganismsDatabaseStatus
catA1chloramphenicol acetyltransferase
chloramphenicol
  • Staphylococcus aureus
  • Enterococcus faecium
ReslitNot Validated
dfrAdihydrofolate reductase
trimethoprim
  • Escherichia coli
  • Klebsiella pneumoniae
ReslitNot Validated
ere(A)macrolide esterase
macrolides
  • Escherichia coli
  • Staphylococcus aureus
ReslitNot Validated
ere(B)macrolide phosphotransferase
macrolides
  • Escherichia coli
  • Staphylococcus aureus
ReslitNot Validated
erm(A)erythromycin ribosome methylase
macrolideslincosamidesstreptogramin b
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Streptococcus pyogenes
ReslitNot Validated
erm(B)erythromycin ribosome methylase
macrolideslincosamidesstreptogramin b
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Streptococcus pyogenes
ReslitNot Validated
erm(C)erythromycin ribosome methylase
macrolideslincosamidesstreptogramin b
  • Staphylococcus aureus
  • Streptococcus pyogenes
ReslitNot Validated
linalincomycin nucleotidyltransferase
lincomycin
  • Staphylococcus aureus
  • Staphylococcus epidermidis
ReslitNot Validated
linblincomycin nucleotidyltransferase
lincomycin
  • Enterococcus faecium
ReslitNot Validated
mecApenicillin-binding protein
methicillin
  • Staphylococcus aureus
  • coagulase-negative staphylococci
ReslitNot Validated
mef(A)macrolide efflux pump
macrolides
  • Streptococcus pyogenes
  • Streptococcus pneumoniae
ReslitNot Validated
mef(En2)macrolide efflux pump
macrolides
  • Streptococcus pneumoniae
ReslitNot Validated
msr(A)macrolide and streptogramin B efflux pump
macrolidesstreptogramin b
  • Staphylococcus aureus
ReslitNot Validated
msrbmacrolide and streptogramin B efflux pump
macrolidesstreptogramin b
  • Staphylococcus aureus
ReslitNot Validated
mupAmupirocin-resistant isoleucyl-tRNA synthetase
mupirocin
  • Staphylococcus aureus
  • Coagulase-negative staphylococci
ReslitNot Validated
satAstreptogramin A acetyltransferase
streptogramin a
  • Enterococcus faecium
ReslitNot Validated
tet(K)efflux pump
tetracyclinedoxycyclineminocycline
  • Staphylococcus aureus
  • Enterococcus faecium
ReslitNot Validated
tet(L)efflux pump
tetracyclinedoxycyclineminocycline
  • Staphylococcus aureus
ReslitNot Validated
tet(M)ribosomal protection protein
tetracyclinedoxycyclineminocycline
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Enterococcus faecium
ReslitNot Validated
tet(O)ribosomal protection protein
tetracyclinedoxycyclineminocycline
  • Streptococcus pneumoniae
ReslitNot Validated
vanAd-Ala-d-Ala ligase
vancomycinteicoplanin
  • Enterococcus faecium
ReslitNot Validated
vanBd-Ala-d-Ala ligase
vancomycin
  • Enterococcus faecium
ReslitNot Validated
vanCd-Ala-d-Ser ligase
vancomycin
  • Enterococcus flavescens
  • Enterococcus casseliflavus
ReslitNot Validated
vanC1d-Ala-d-Ser ligase
vancomycin
  • Enterococcus gallinarum
ReslitNot Validated
vat(A)streptogramin A modifying enzyme
streptogramin a
  • Staphylococcus aureus
  • Streptococcus pyogenes
ReslitNot Validated
vgb(A)streptogramin B modifying enzyme
streptogramin b
  • Staphylococcus aureus
  • Streptococcus pyogenes
ReslitNot Validated